Blood Clot Discovery Might Offer Better Treatments For Blood Diseases
Researchers have found novel ways in which the body can regulate blood clots, in the innovation which might offer better treatments. These treatments could assist avoid and treat numerous health conditions. It includes stroke, heart diseases, and vascular dementia. This research was headed by the University of Exeter. It was supported by the British Heart Foundation. The research team has invented a novel technique that lets them to concurrently measure blood clotting and the development of free radicals.
Free radicals are unsteady molecules that contain unpaired single electrons in quest of pairing up. This situation makes these molecules extremely reactive and offers them an ability to alter lipids, protein, and DNA. Among other unnecessary effects, free radicals take a part in the blood clots build-up. These blood clots, in turn, are believed to be an important driver in the formation of numerous conditions. It includes stroke, heart disease, dementia, and inflammation-associated conditions such as arthritis.
On a similar note, Alzheimer’s disease is the most widespread reason for dementia, with more than half a million patients in the U.K. alone. It is said to be a progressive disease, which is differentiated by difficulties with thinking, language, or problem-solving, and memory loss. The condition is distinguished by a decrease in the number of connections between neurons in the brain, triggered by the build-up of the protein as tangles and plaques. Ultimately, this protein build-up results in the breakdown of synapses and cognitive rejection.
Earlier researches have demonstrated anomalies in the huge network of blood vessels in the brain. However, it was unclear if the vascular damage added to synaptic damage or whether it triggered neuroinflammation, both of which can lead to cognitive rejection. At present, employing state-of-the-art imaging technology, researchers from the Gladstone Institutes have created the foremost 3-dimensional volume images of Alzheimer’s disease.